A liver transplant may significantly impact production of some coagulation factors. Some patients develop a coagulation deficiency after a liver transplant.
(1) no evidence of a coagulation factor deficiency prior to the liver transplant
(2) presence of the deficiency after the liver transplantation
This has been reported for:
(1) Factor VIII
(2) Factor XI
(3) Factor VII
(4) Factor XII
There are 2 possible mechanisms:
(1) the liver donor had an unrecognized coagulation factor deficiency with deficient production by the liver
(2) production an anti-factor antibody, possibly by lymphocytes in the transplanted liver
(1) consumptive coagulopathy related to rejection or infection
(2) unrecognized factor deficiency in the recipient unmasked by the transplant
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Purpose: To evaluate a patient who developed a coagulation factor deficiency after undergoing a liver transplant.
Specialty: Hematology Oncology, Clinical Laboratory, Surgery, general
Objective: laboratory tests, complications
ICD-10: D65-D69, T86.4, Y83.0, Y83.4, Z94.4,