Description

Garey et al developed an index for identifying a patient at risk for Clostridium difficile infection (CDI). This can help to identify a patient who may benefit from more aggressive management or a change in antibiotic therapy. The authors are from the University of Houston, University of Texas Houston, Baylor College of Medicine and St. Luke’s Episcopal Hospital.


 

Patient selection: hospitalized adult (>= 18 years old) receiving broad-spectrum antibiotics.

 

The authors reported two risk indices, one simple and one based on the odd ratios (OR) for the risk factors.

 

Parameters:

(1) age in years

(2) hemodialysis

(3) admission type

(4) number of weeks in the ICU

Parameter

Finding

Points for Simple

Points for OR Index

age

< 50 years

0

0

 

50 to 80 years

1

1.5

 

> 80 years

2

2.5

hemodialysis

no

0

0

 

yes

1

1.5

admission type

surgical

0

0

 

other (non-surgical)

1

2

number of weeks in ICU

 

<weeks>

2 * <weeks>

 

where:

• The number of weeks in the ICU need not be a whole number.

 

total score for simple index =

= SUM(points for all 4 parameters using simple model)

 

total score for OR index =

= SUM(points for OR model)

 

Interpretation:

• minimum simple or OR index: 0

• maximum simple index: 4 + (number of weeks in ICU)

• maximum OR index: 6 + (2 * (number of weeks in ICU)

 

Total Simple Score

Total OR Score

Risk level

< 3

0 to 3

low

3 to 4

> 3 to 9.0

moderate

> 4 to 6

> 9 to 11.5

high

> 6

> 11.5

very high

 


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