Clinical findings:
(1) prolonged erection of the clitoris not associated with sexual arousal
(2) burning, discomfort, pain and/or tenderness in the clitoris, vulva and adjacent structures
(3) discoloration of the clitoris (erythema, cyanosis, other)
Risk factors:
(1) pelvic malignancy (urinary bladder, cervix, uterus, ovary)
(2) drugs (bupropion, citalopram, nefazodone, fluoxetine, trazadone or other antidepressants; any drug with alpha-1 adrenergic blocking ability)
(3) congenital clitoromegaly
Therapy includes:
(1) If drug-related, discontinuation of drug.
(2) If tumor-related, treatment of tumor.
(3) Injection of a small amount of dilute epinephrine into the dilute epinephrine (1:100,000) and heparin (500 U/mL) into the shaft and crura.
(4) Therapy with an alpha-adrenergic agonist (phenylephrine, phenylpropanolamine).
