Clinical Symptoms of Hypopituitarism in Children

 

Endrocrine axes that may be affected:

(1) corticotropin

(2) thyrotropin

(3) growth hormone

(4) gonadotropin

(5) vasopressin

 

Features of corticotropin deficiency (adrenocortical insufficiency0:

(1) growth retardation

(2) fatigue, tiredness and weakness

(3) dizziness

(4) nausea and vomiting

(5) anorexia and weight loss

(6) pallor

(7) hypoglycemia

(8) circulatory collapse

 

Features of thyrotropin deficiency (hypothyroidism):

(1) decreased sweating

(2) coarse, dry skin

(3) cold intolerance

(4) constipation

(5) hoarseness

(6) decreased hearing

(7) slow movements

(8) decreased deep tendon reflexes

(9) paresthesias

(10) bradycardia

 

Features of growth hormone deficiency:

(1) growth retardation

 

Features of gonadotropin deficiency:

(1) delayed puberty

 

Features of vasopressin deficiency (diabetes insipidus):

(1) large volumes of urine with a low osmolality