Description

Arends et al reported a clinical prediction rule for predicting survival for a patient with hypopharynx cancer. The authors are from The Netherlands Cancer Institute, Amsterdam UMC, University Medical Center Utrecht, University of Amsterdam and Academic Medical Center Amsterdam.


Patient selection: hypopharynx cancer

 

Parameters:

(1) location in the pyriform sinus

(2) T status

(3) N status

(4) ACE27 score

(5) body mass index (BMI) in kg per square meter, from 10 to 45

(6) hemoglobin in mmol/L, from 4 to 11.5 (use conversion factor 0.6206 for g/dL to mmol/L)

(7) serum albumin in g/L, from 15 to 60

(8) leukocytosis (WBC >= 10.5 * 10^9/L)

 

points for BMI =

= 67.076 - (1.49 * (BMI))

 

points for hemoglobin =

= 100.58 - (8.746 * (hemoglobin))

 

points for serum albumin =

= 133.333 - (2.222 * (albumin))

 

Parameter

Finding

Points

location in pyriform sinus

no

0

 

yes

1.86

T status

T1 or T2

0

 

T3

7.7

 

T4

50.9

N status

N0 or N1

0

 

N2

51.2

 

N3

65.2

ACE27

0

0

 

1

27

 

2

52.9

 

3

68.1

leukocytosis

no

0

 

yes

0.31

 

total score =

= SUM(points for all of the parameters)

 

Interpretation:

minimum score: 0

maximum score: 403.2

 

Total Score

Risk of Mortality

< 155

low risk

155 to 201

medium risk

> 201

high risk

 


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