Children with Reye's Syndrome can be staged clinically by their signs and symptoms.
Findings evaluated:
(1) level of consciousness
(2) posture
(3) response to painful stimuli
(4) pupillary response to light
(5) oculocephalic reflex (doll's eyes)
Finding |
Stage 0 |
Stage I |
Stage II |
level of consciousness |
normal |
lethargic but follows verbal commands |
combative to stuporous; verbalizes inappropriately |
posture |
normal |
normal |
normal |
response to painful stimuli |
purposeful |
purposeful |
purposeful to nonpurposeful |
pupillary reaction to light |
brisk |
brisk |
sluggish |
oculocephalic reflex (doll's eyes) |
normal |
normal |
conjugate deviation of eyes |
Finding |
Stage III |
Stage IV |
Stage V |
level of consciousness |
comatose |
comatose |
comatose |
posture |
decorticate |
decerebrate |
flaccid |
response to painful stimuli |
decorticate |
decerebrate |
no response |
pupillary reaction to light |
sluggish |
sluggish |
no response |
oculocephalic reflex (doll's eyes) |
conjugate deviation of eyes |
inconsistent or no response |
no response |
where (Plum and Posner, 1982):
• decorticate posture = abnormal flexor response in the arm with extension of the leg
• decerebrate posture = abnormal extensor response in the arms and legs
• oculocephalic reflex = First, one holds the patient's eyelids open and briskly rotates the head from one side to the other. A positive response is contraversive conjugate eye deviation (if the head is rotated to the left, the eyes deviate to the right). Then the neck is briskly flexed and then extended. A positive response is deviation of the eyes upward when the neck is flexed and downward when the neck is extended. The doll's head phenomenon is the opening of the eyelids reflexly when the neck is flexed.
Specialty: Gastroenterology, Pedatrics, Pharmacology, clinical