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Description

Hemorrhagic fever with renal syndrome (HFRS) due to a Hantavirus infection is staged based on clinical findings.


Patient selection: hantavirus-associated hemorrhagic fever with renal syndrome

 

Route of exposure: inhalation of aerosolized rodent secretions

 

Clinical features: fever, hemorrhage, renal dysfunction, variable hypotension

 

The febrile stage is defined by a body temperature >= 37.3°C, which typically lasts 4-7 days.

 

The hypotensive shock stage is defined as systolic blood pressure <= 90 mm Hg, which typically occurs 4-6 days after disease onset.

 

Nonfebrile renal stages are based on 24-hour urine output.

 

24-Hour Urine Output

Nonfebrile Renal Stage

< 400 mL

oliguric stage

> 2,000 mL

polyuric stage

<= 2,000 mL

recovery stage

 


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