Description

Jansson et al developed a clinical score for the diagnosis of nonbacterial osteitis (NBO). The score can be used along with other clinical information to reach a final diagnosis. The authors are from Ludwig Maximilian University in Munich.


Patient selection: pediatric and adult

 

Parameters:

(1) blood cell count (presumed to be the complete blood count, CBC)

(2) symmetry of lesions

(3) lesions with marginal sclerosis

(4) body temperature

(5) lesions location

(6) number of radiologically-proven lesions

(7) serum C-reactive protein in mg/dL

 

Parameter

Findings

Points

CBC

normal

13

 

abnormal

0

symmetry

symmetrical

10

 

assymmetrical

0

marginal sclerosis in lesions

absent

0

 

present

10

body temperature

normal (afebrile)

9

 

abnormal

0

location of lesions

vertebrae, clavicles, sternum

8

 

other bones

0

number of radiologically-proven lesions

0 or 1

0

 

>= 2

7

serum CRP

< 1 mg/dL

0

 

>= 1 mg/dL

6

 

total score =

= SUM(points for all 7 parameters)

 

Interpretation:

• minimum score: 0

• maximum score: 63

• The higher the score the greater the likelihood of NBO.

 

Score

Diagnosis

Performance

<= 28

probably not

NPV 97%

29 to 38

uncertain

80% NBO

>= 39

probably NBO

PPV 97%, sensitivity 68%

 


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