de Moraes et al reported a score for predicting chronic arthralgia following infection with Chikungunya virus (CHIKV). This can help to identify a patient who may benefit from an intervention. The authors are from multiple institutions in Brazil, California and Belgium.
SHERA is an acronym sex, hypertension, edema, retro-ocular pain and age.
Outcome: persistent arthralgia after 12 months
Parameters:
(1) edema
(2) hypertension
(3) retro-orbital pain
(4) age in years
(5) sex
Parameter
Finding
Points
edema
no
0
yes
2.5
hypertension
no
0
yes
2
retro-orbital pain
no
0
yes
2
age in years
<= 26 years
0
> 26 years
1.5
sex
male
0
female
1
total score =
= SUM(points for all 5 parameters)
Interpretation:
• minimum score: 0
• maximum score: 9
• A score >= 5 is associated with a high risk of persistent arthralgia.
Performance:
• The area under the ROC curve was 0.91 for the derivation and 0.83 for the validation cohort.
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