Kuipers et al reviewed the risk of venous thrombosis after air travel in light of clinical risk factors. A patient at high risk may benefit from more aggressive management. The authors are from Leiden University Medical Center and Academic Medical Centre Amsterdam.
Patient selection: person with or without air travel
Parameters:
(1) surgery
(2) malignancy
(3) plaster cast
(4) oral contraceptive
(5) hormone replacement therapy
(6) pregnancy
(7) recent delivery
Parameter
Finding
Odds Ratio
surgery
negative
1
air travel
2.1
other risk factor
9.1
air travel and risk factor
19.8
malignancy
negative
1
air travel
2
other risk factor
8.8
air travel and risk factor
18
plaster cast
negative
1
air travel
2.1
other risk factor
23.9
air travel and risk factor
24.4
oral contraceptive
negative
1
air travel
2.5
other risk factor
3.2
air travel and risk factor
8.2
hormone replacement
negative
1
air travel
2.2
other risk factor
1
air travel and risk factor
6.8
pregnancy
negative
1
air travel
2.6
other risk factor
4.3
air travel and risk factor
14.3
recent delivery
negative
1
air travel
2.9
other risk factor
10.2
air travel and risk factor
NA (use 10.2)
cumulative odds ratio =
= PRODUCT(OR for all parameters)
Interpretation:
• minimum cumulative odds ratio: 1
• maximum cumulative odds ratio: 70,727,05
• The impact of actions to reduce risk are not included.
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