The clinical presentation of a foregut duplication cyst depends on its size, location and mucosal line.
Foregut: pharynx, esophagus, stomach, proximal first and second parts of the duodenum
On imaging a cystic structure is typically seen.
A large duplication cyst may compress adjacent structures:
(1) a pharyngeal cyst may obstruct the airway
(2) a cyst in the mediastinum may compress the left atrium
(3) a very large intrathoracic cyst may compress the lungs
Signs and symptoms may include:
(1) none (asymptomatic)
(2) respiratory distress and/or stridor
(3) recurrent abdominal pain or vomiting
(4) mass: palpable mass, lingual mass, neck mass
(5) palpitations
(6) difficult feeding
If the cyst shows gastric mucosa, then peptic ulceration or malignancy may develop. Other tissue (thymus, enteric mucosa, etc).
