Chayangsu et al reported a clinical prediction for identifying a patient with non-small cell lung cancer who is more likely to respond to chemotherapy. The authors are from Suranaree University of Technology, Chiang Mai University, and Chulalongkorn University in Thailand.
Patient selection: non-small cell lung cancer (NSCLC)
Parameters:
(1) gender
(2) age in years
(3) smoking status
(4) ECOG performance status
(5) serum albumin in g/dL
(6) histologic subtype
Parameter
Finding
Points
gender
male
0
female
4
age in years
< 60 years
0
>= 60 years
1
smoking status
current
2
former
2
never
0
ECOG performance
0 or 1
1
>= 2
0
serum albumin
>= 3.5 g/dL
2.5
< 3.5 g/dL
0
histologic subtype
squamous cell carcinoma
2.5
non-squamous cell
0
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: 0
• maximum score: 13
Total Score
Risk Category
Percent Responding
0 to 8
low
50%
8.5 to 13
high
84%
Performance:
• The area under the ROC curve is 0.71.
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