Patient selection: preterm neonate
Parameters:
(1) preeclampsia
(2) small for gestational age (SGA)
(3) clinical chorioamnionitis
(4) gestational age in weeks
(5) preterm premature rupture of the membranes (PPROM)
(6) delivery
|
Parameter
|
Finding
|
Score 1
|
Score 2
|
|
preeclampsia
|
no
|
3
|
2
|
|
|
yes
|
0
|
0
|
|
SGA
|
no
|
3
|
1
|
|
|
yes
|
0
|
0
|
|
chorioamnionitis
|
no
|
0
|
0
|
|
|
yes
|
2
|
1
|
|
gestational age
|
<= 28 weeks
|
2
|
NA
|
|
|
> 28 weeks
|
0
|
NA
|
|
|
<= 27 weeks
|
NA
|
1
|
|
|
> 27 weeks
|
NA
|
0
|
|
PPROM
|
no
|
0
|
0
|
|
|
yes
|
1
|
1
|
|
delivery
|
vaginal
|
1
|
NA
|
|
|
Cesarean
|
0
|
NA
|
score 1 = histologic evidence of chorioamnionitis =
= SUM(points for all 6 parameters)
score 2 = histologic evidence of chorioamnionitis with fetal involvement =
= SUM(points for the first 5 parameters)
Interpretation:
• minimum for scores: 0
• maximum for score 1: 12
• maximum for score 2: 6
• Score 1 >= 7 indicates a positive result.
• Score 2 >= 4 indicates a positive result.
Performance:
• The area under the ROC curve for score 1 was 0.95 in the derivation group and 0.81 in the validation group.
• The area under the ROC curve for score 2 was 0.92 in the derivation group and 0.83 in the validation group.
