BAC-HD = body temperature, alkaline phosphatase, CRP, heart rate, drug)
Patient selection: outpatient maintenance hemodialysis
Outcome: bacteremia (present in 16% of study cohort)
Parameters:
(1) body temperature in °C
(2) heart rate in beats per minute
(3) serum CRP in mg/dL
(4) serum alkaline phosphatase in IU/L
(5) prior antibiotics within 1 week
|
Parameters
|
Findings
|
Points
|
|
body temperature
|
< 38.3°C
|
0
|
|
|
>= 38.3°C
|
1
|
|
heart rate
|
< 125 beats per minute
|
0
|
|
|
>= 125 beats per minute
|
1
|
|
serum CRP
|
< 10 mg/dL
|
0
|
|
|
>= 10 mg/dL
|
1
|
|
serum alkaline phosphatase
|
<= 360 IU/L
|
0
|
|
|
> 360 IU/L
|
1
|
|
prior antibiotics within 1 week
|
yes
|
0
|
|
|
no
|
1
|
total score =
= SUM(points for all 5 parameters)
Interpretation:
• minimum score: 0
• maximum score: 5
• A score >= 2 is associated with an increased risk of bacteremia.
Performance:
• A score >= 2 has a sensitivity of 90% and specificity of 51%.
• The area under the ROC curve is 0.76.
