Jameran et al reported a clinical prediction rule for predicting candidemia in a critically-ill patient. This can help to identify a patient who should be monitored more closely, allowing for early diagnosis. The authors are from Universiti Kebandsaan Malaysia Medical Centre in Kuala Lumpur.
Patient selection: critically-ill patient with candidemia
Parameters:
(1) acute kidney injury
(2) renal replacement therapy
(3) parenteral nutrition
(4) multifocal colonization with Candida species (on survey cultures)
Parameter
Finding
Points
acute kidney injury
no
0
yes (OR 7.7)
2
renal replacement therapy
no
0
yes (OR 52.8)
4
parenteral nutrition
no
0
yes (OR 63.7)
4
multifocal colonization
no
0
yes (OR 23.6)
3
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: 0
• maximum score: 13
• A cutoff of 5.1 has a sensitivity of 80% and specificity of 77%.
Performance:
• The area under the ROC curve is 0.91.
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