Genders et al reported a clinical prediction rule for the diagnosis of coronary artery disease (CAD). The authors are from multiple institutions in Europe and the United States.
Coronary artery disease was defined as >= 1 coronary artery with >= 50% lumen diameter reduction.
Parameters:
(1) age in years
(2) sex
(3) chest pain
Parameter
Finding
Points
age
0.04 * (age)
sex
female
0
male
1.34
chest pain
typical
1.91
atypical
0.64
nonspecific
0
X =
= SUM(points for the 3 parameters) - 4.37
probability of coronary artery disease =
= 1 / (1 + EXP((-1) * X))
Performance:
• The area under the ROC curve is 0.79.
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