Description

Chavanet et al reported a clinical prediction rule referred to as Meningitest which can distinguish bacterial from viral meningitis. The authors are from multiple institutions in France, Spain and the United States.


NOTE: This is distinct from the Meningitest of Dubos et al.

 

Parameters:

(1) white blood cell count per microliter

(2) CSF leukocyte count per microliter

(3) percent PMNs in the CSF differential count

(4) CSF protein concentration in g/L

(5) ratio of glucose in CSF to blood

 

ratio of glucose in CSF to blood =

= (CSF glucose in mg/dL) / (blood glucose in mg/dL)

 

Parameter

Finding

Points for Adult (> 15 yo)

WBC count

<= 15,000 per µL

0

 

> 15,000 per µL

3

CSF WBC count

> 1700 per µL

4

 

251 to 1700

2

 

<= 250

1

CSF PMNs

> 90%

4

 

81 to 90%

2

 

26 to 80%

1

 

<= 25%

0

CSF protein

> 2.3 g/L

5

 

0.81 to 2.3

2

 

<= 0.8

0

CSF/blood glucose ratio

<= 0.35 (< 0.33 in abstract)

4

 

> 0.35

0

 

total score for an adult =

= SUM(points for all 5 parameters)

 

Parameter

Finding

Points for Child (> 3 months to 15 yo)

CSF WBC count

>= 1800 per µL

2

 

< 1800

0

CSF PMNs

> 80%

3

 

<= 80%

0

CSF protein

> 1.2 g/L

3

 

<= 1.2 g/L

0

CSF/blood glucose ratio

<= 0.3 (< 0.3 in abstract)

3

 

> 0.3

0

 

total score for a child =

= SUM(points for all 4 parameters)

 

Interpretation:

minimum score for an adult: 1

maximum score for an adult: 20

A score >= 6 for an adult indicates bacterial meningitis.

minimum score for a child: 0

maximum score for a child: 11

A score >= 2 for a child indicates bacterial meningitis.


To read more or access our algorithms and calculators, please log in or register.