Al-Ani et al reported a clinical prediction rule for venous thromboembolism in a patient with acute leukemia. This can help to identify a patient who may benefit from interventions to reduce the risk of thrombosis. The authors are from Western University in London, Ontariio.
Patient selection: acute leukemia
Parameters:
(1) history of previous venous thromboembolism (VTE)
(2) type of acute leukemia
(3) platelet count in 10^9/L
Parameter
Finding
Points
previous history of VTE
no
0
yes
3
type of acute leukemia
lymphoblastic
2
other
0
platelet count
> 50 * 10^9/L at diagnosis
1
<= 50 * 10^9/L at diagnosis
0
total score =
= SUM(points for all 3 parameters)
Interpretation:
• minimum score: 0
• maximum score: 6
• A score >= 3 indicates high risk, with a cumulative incidence of 44%.
• A score < 3 is low risk, with a cumulative incidence of 11%.
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