Figueroa-Phillips et al reported a model for predicting central line-associated bloodstream infection (CLABSI) in a pediatric patient with a central line who is presenting to the Emergency Department. The authors are from the Children's Hospital of Philadelphia and the University of Pennsylvania.
Patient selection: pediatric patient presenting to the Emergency Department, <= 18 years of age
Parameter:
(2) race
(3) total parenteral nutrition (TPN)
(4) tunneled CVC
(5) double lumen central line
(6) other bacterial infection
(7) viral upper respiratory infection symptoms
(8) diarrhea
(9) temperature in °C in the Emergency Department
(10) fever prior to presentation
(11) absolute neutrophil count per microliter
(12) season of the year
Parameter |
Finding |
Points |
age in yars |
<= 5 |
1 |
|
> 5 |
0 |
race |
Black |
2 |
|
other |
0 |
TPN |
no |
0 |
|
yes |
3 |
tunneled catheter |
no |
0 |
|
yes |
4 |
double lumen catheter |
no |
0 |
|
yes |
2 |
other bacterial infection |
no |
2 |
|
yes |
0 |
viral upper respiratory |
no |
2 |
|
yes |
0 |
diarrhea |
no |
0 |
|
yes |
2 |
temperature |
< 39.5°C |
0 |
|
>= 39.5°C |
2 |
fever prior to presentation |
no |
0 |
|
yes |
2 |
absolute neutrophil count |
>= 500 per µL |
0 |
|
< 500 per µL |
3 |
season |
spring or summer |
1 |
|
fall or winter |
0 |
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: 0
• maximum score: 26
• A score < 6 had a negative predictive value of 99.2% for CLABSI.
• The higher the score the greater the risk for CLABSI.
• The maximum Youden index was seen with 8 and 9 (0.439).
Performance:
• The area under the ROC curve is 0.81.
Specialty: Infectious Diseases