Description

Figueroa-Phillips et al reported a model for predicting central line-associated bloodstream infection (CLABSI) in a pediatric patient with a central line who is presenting to the Emergency Department. The authors are from the Children's Hospital of Philadelphia and the University of Pennsylvania.


Patient selection: pediatric patient presenting to the Emergency Department, <= 18 years of age

 

Parameter:

(1) age in years

(2) race

(3) total parenteral nutrition (TPN)

(4) tunneled CVC

(5) double lumen central line

(6) other bacterial infection

(7) viral upper respiratory infection symptoms

(8) diarrhea

(9) temperature in °C in the Emergency Department

(10) fever prior to presentation

(11) absolute neutrophil count per microliter

(12) season of the year

 

Parameter

Finding

Points

age in yars

<= 5

1

 

> 5

0

race

Black

2

 

other

0

TPN

no

0

 

yes

3

tunneled catheter

no

0

 

yes

4

double lumen catheter

no

0

 

yes

2

other bacterial infection

no

2

 

yes

0

viral upper respiratory

no

2

 

yes

0

diarrhea

no

0

 

yes

2

temperature

< 39.5°C

0

 

>= 39.5°C

2

fever prior to presentation

no

0

 

yes

2

absolute neutrophil count

>= 500 per µL

0

 

< 500 per µL

3

season

spring or summer

1

 

fall or winter

0

 

total score =

= SUM(points for all of the parameters)

 

Interpretation:

minimum score: 0

maximum score: 26

A score < 6 had a negative predictive value of 99.2% for CLABSI.

The higher the score the greater the risk for CLABSI.

The maximum Youden index was seen with 8 and 9 (0.439).

 

Performance:

The area under the ROC curve is 0.81.


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