Went et al proposed a clinical-pathologic prognostic score for patients with peripheral T-cell lymphomas. This can help identify patients who may benefit from more aggressive management. The authors are from the University of Bologna, Perugia University, University of Pavia, University of Modena, University of Basel and the Intergruppo Italiano Linformi.
Parameters:
(1) age in years
(2) serum lactate dehydrogenase (LDH)
(3) performance status
(4) percent Ki-67 positive cells
Parameter
Finding
Points
age in years
<= 60 years of age
0
> 60 years of age
1
serum LDH
normal
0
high
1
performance status
ECOG 0 or 1
0
ECOG 2, 3 or 4
1
percent Ki-67 positive cells
< 80%
0
>= 80%
1
total score =
= SUM(points for all 4 parameters)
Interpretation:
• minimum score: 0
• maximum score: 4
• The higher the score the worse the outcome.
Total Score
Group
Median Survival
0 or 1
I
37 months
2
II
23 months
3 or 4
III
6 months
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