Description

Hegedus listed several clinical findings which are suspicious for thyroid carcinoma in a euthyroid patient with a solitary thyroid nodule. These can help identify a patient who may benefit from a more complete evaluation. The author is from Odense University Hospital in Denmark.


 

Clinical Finding

Level of Risk

age of the patient < 20 or > 70 years of age

moderate

male gender

moderate

family history of medullary thyroid carcinoma

high

family history of an MEN syndrome

high

history of neck irradiation

moderate

presence of dysphagia, dysphonia, hoarseness, dyspnea and/or cough

moderate

paralysis of the vocal cords

high

rapid nodule growth, especially during levothyroxine therapy

high

nodule > 4 cm in diameter

moderate

nodule that is partially cystic

moderate

nodule that is very hard or firm

high

nodule fixated to adjacent structures

high

regional lymphadenopathy

high

distant metastases

very high

 


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