Absorption of epinephrine used as vasoconstricting agent during surgery can result in a number of clinical findings, some of which are serious.
Clinical findings of epinephrine intoxication:
(1) ventricular tachyarrhythmias with or without tachycardia
(2) pulmonary edema with hypoxemia
(3) heart failure
(5) intracerebral hemorrhage
Some findings occur immediately while others such as pulmonary edema may be delayed.
A patient receiving a dilute epinephrine solution to reduce blood loss should be carefully monitored during and after the exposure.
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Specialty: Hematology Oncology, Clinical Laboratory, Pharmacology, clinical