Inflammatory cardiomyopathy (ICM) can be diagnosed based on clinical findings identified..
Clinical findings:
(1) duration of symptoms > 30 days
(2) chest pain
(3) heart failure
(4) palpitations
(5) syncope
(6) history of myocarditis
Laboratory findings:
(1) variable increase in serum troponin
(2) variable positive PCR for causative microorganism
ECG:
(1) atrioventricular block and/or bundle branch block
(2) ST and T wave changes
(3) supraventricular or ventricular arrhythmias
(4) abnormal Q waves
(5) low voltage QRS complex
Echocardiography:
(1) dilatation of left and/or right ventricle
(2) usually normal ventricular wall thickness
(3) impaired ventricular function with reduced LVEF
(4) pericardial effusion
Cardiac MRI:
(1) >= 2 (out of 3) Lake Louise criteria for myocarditis
(2) variable myocyte edema
(3) late gadolinium enhancement
Endomyocardial biopsy:
(1) variable inflammatory infiltrate in endomyocardial biopsy
(2) fibrosis
(3) myocyte abnormalities
