Rejection occurs in a 20-30% of patients who receive a corneal graft. Early recognition and corticosteroid therapy can preserve the graft in some cases.


Clinical symptoms:

(1) feeling of irritation in the eye with the corneal graft

(2) blurred vision


Clinical findings

(3) injection (congestion, hyperemia) of the eye

(4) stromal edema

(5) anterior chamber reaction

(6) keratoprecipitates in the grafted cornea

(7) Khodadoust line running across the grafted cornea



• A Khoudadoust line is formed by the advancing infiltrate of inflammatory cells, with normal cornea on one side and an inflammatory reaction on the other.


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