Medication-induced esophageal injury (MIEI) may present with a number of clinical findings that vary with the severity of the injury.


Clinical findings may include:

(1) unexplained nausea and vomiting

(2) heartburn or retrosternal pain

(3) odynophagia (painful swallowing)

(4) dysphagia

(5) unintended weight loss

(6) abdominal pain

(7) hematemesis

(8) fever

(9) dehydration due to decreased oral fluid intake


The presence of clinical findings in a person taking oral medication with risk factors for medication-induced esophageal injury (above) should prompt a clinical investigation including endoscopy and/or double contrast barium swallow.


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