A patient with idiopathic inflammatory bowel disease (IBD - Crohn's disease or ulcerative colitis) may develop a chronic tracheobronchitis.
(1) tends to affect young women
(2) may correlate with an exacerbation of the IBD
(1) dry or productive cough
(2) dyspnea on exertion
(1) mild leukocytosis
(2) elevation in erythrocyte sedimentation rate (ESR) or C-reactive protein (CRP)
(3) inflammation in sputum and/or bronchial washings
Respiratory function testing:
(1) upper airway obstructive pattern in the flow-volume loop
(2) hyperresponsive bronchi
Imaging studies should not show an infiltrate in the lung fields unless there is another process such as pneumonia or pneumonitis.
Bronchoscopy may show:
(1) inflammation of the airway mucosa
(2) stenosis in the upper airway
Complications may include:
(1) progression to respiratory failure
(2) stenosis of the upper airway
(1) chronic bronchitis associated with COPD
(2) infectious bronchitis
(3) pulmonary toxicities of medications
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Specialty: Pulmonology, Immunology/Rheumatology