The solitary rectal ulcer syndrome (SRUS, mucosal prolapse syndrome) is believed to occur due to shear injury to the rectal mucosa that prolapses during defecation. It is often misdiagnosed, usually for a period of time.


It can occur at any age but is more common in young to middle-aged adults.


It is more common in women.


Clinical findings may include:

(1) abdominal or perineal pain, especially during defecation

(2) constipation with or without a sense of obstruction

(3) a history of straining at stool

(4) variable history of rectal bleeding

(5) variable history of digital disimpaction

(6) mucous discharge

(7) variable presence of a palpable mass lesion or an area of induration on the anterior rectal wall

(8) variable diarrhea or loose stools


Many patients are misdiagnosed as having:

(1) Crohn's disease

(2) ulcerative colitis

(3) rectal carcinoma

(4) adenomatous polyps

(5) suppository-related injury


To read more or access our algorithms and calculators, please log in or register.