The loose anagen syndrome is associated with increased hair loss, typically in children. It can be diagnosed based on clinical findings and microscopic features of the hair.
Clinical findings:
(1) It affects fair haired individuals.
(2) The hair is easily dislodged by pulling on the hair.
(3) The hair may be unruly.
(4) It is usually recognized in childhood but may persist into adulthood.
(5) It may be familial and may affect the parents of affected children.
Microscopic features of the hair:
(1) The proximal end shows a normal anagen bulb.
(2) The cuticle is ruffled.
(3) The root sheath is not attached
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