The diencephalic syndrome (Russell syndrome) is a rare cause for failure to thrive in an infant or young child.
Causes of the diencephalic syndrome may include:
(1) glioma in the region of the optic chiasm or hypothalamus
(2) midline cerebellar astrocytoma
(3) suprasellar tumor (ependymoma, spongioblastoma)
(4) thalamic tumor
Clinical features may include:
(1) failure to thrive
(2) emaciation (cachexia) despite normal caloric intake
(7) nystagmus or strabismus
(8) visual field defect
(9) optic pallor
(12) no evidence of malabsorption
To read more or access our algorithms and calculators, please log in or register.