Orofacial granulomatosis (OFG) is a disorder of uncertain etiology that is associated with a number of clinical findings.
Clinical finding:
(1) facial swelling
(2) swelling of the upper and/or lower lips
(3) mucosal edema
(4) angular cheilitis
(5) oral ulcerations
(6) allergy to food or food additives
A biopsy shows noncaseating granulomas.
Diagnosis requires exclusion of other causes of granulomatous inflammation:
(1) Crohn's disease
(2) sarcoidosis
(3) Melkersson-Rosenthal syndrome
(4) tuberculosis
(5) foreign body reaction
(6) deep fungal infection
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Specialty: Otolaryngology
