A patient with folate deficiency may develop a number of clinical and laboratory findings.


Clinical features:

(1) clinical anemia (pallor, fatigue, tiredness, etc)

(2) depapillation and/or soreness of the tongue

(3) anorexia

(4) diarrhea

(5) forgetfulness

(6) behavioral changes (irritability, paranoia, etc)

(7) neural tube defects (in the fetus)


Laboratory findings:

(1) anemia with elevated MCV

(2) decreased serum folate concentration


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