Eosinophilic esophagitis may occur in both children and adults. In children asthmatic symptoms and food allergy tend to be prominent.
Clinical findings (pattern varies with age):
(1) feeding disorder (young child)
(4) food impaction (during adolescence)
(5) abdominal pain
(6) refractory gastroesophageal reflux disease (GERD)
(7) food allergy, with clinical improvement on dietary restrictions
(8) asthma and/or rhinosinusitis and/or atopic dermatitis
(1) peripheral eosinophilia
(2) elevated immunoglobulin E
(3) demonstration of food allergy (RAST, other)
The endoscopic appearance may be normal or abnormal. A biopsy from the esophagus shows increased eosinophils (> 15 per high powered field, hpf).
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