Duane’s Retraction Syndrome (DRS, Congenital Retraction Syndrome, Stilling-Turk-Duane Retraction Syndrome) is associated with a number of clinical findings.
Clinical features of Duane’s syndrome:
(1) congenital ocular motility disorder
(2) limited abduction and/or adduction
(3) globe retraction on attempted adduction
(4) narrowing of the palpebral fissue on attempted adduction
(5) abnormal vertical eye movements
(1) defect in the development of the abducens nuclei (CN VI)
(2) aberrant innervation of the lateral rectus muscle by branches from the oculomotor nuclei (CN III)
Some cases occur with familial inheritance. Some cases have other congenital anomalies suggesting a teratogenic event in the first trimester of pregnancy.
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