Clinical features:
(1) The patient may notice a persistent painless erythema/injection of the eye.
(2) A lesion is present that may be described as gelatinous, translucent, verrucous, hyperkeratotic/leukoplakic. papilliform.
(3) The lesion may be unilateral or bilateral (bilateral lesions more common with HPV).
(4) The lesion usually occurs along the limbus (junction of the cornea and conjunctiva).
(5) An unusual proliferation of small blood vessels may be present.
(6) The lesion may be pigmented in a darker skinned individual.
(7) Extension over the cornea may cause irritation (gritty, foreign body) and may impair vision.
If the lesion is fixed or immobile, then suspect invasion.
Biopsy is necessary to distinguish it from squamous intra-epithelial neoplasia (dysplasia) or other lesions.
