Collapsing glomerulopathy is associated with a number of clinical findings.
African Americans may have a higher risk for developing collapsing glomerulopathy.
Key clinical features:
(1) marked proteinuria with the nephrotic syndrome
(2) rapid decline in kidney function to end-stage renal disease
(3) poor response to corticosteroid therapy given alone
If an underlying cause cannot be controlled then the prognosis is poor. Control of proteinuria can improve the outcome.
