An overdose of an H1-receptor antagonist may be life-threatening.
Signs and symptoms of central excitation:
(1) excitement and agitation
(2) hallucinations
(3) ataxia
(4) uncoordination
(5) athetosis (involuntary, writhing movements)
(6) seizures
Atropine-like effects:
(1) fixed and dilated pupils
(2) flushed face
(3) sinus tachycardia
(4) urinary retention
(5) dry mouth
(6) fever
Rare:
(1) rhabdomyolysis
(2) prolonged QT interval
Terminal depressant effects:
(1) loss of consciousness with coma
(2) cardiopulmonary collapse
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Specialty: Toxicology, Emergency Medicine, Critical Care
ICD-10: ,
