(2) hypertrophy of Kupffer cells with phagocytized red blood cells
(3) mild centrilobular necrosis
(4) variable cholestasis
Patients with concomitant liver disease (cocaine hepatotoxicity, other) may experience more extensive damage, as manifested by a marked increase in the serum transaminases and more extensive necrosis.
Differential diagnosis:
(1) acute viral hepatitis
(2) toxic hepatopathy
(3) cholelithiasis
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