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Clinical Features and Differential Diagnosis of Bone Marrow Necrosis in a Patient with a Malignancy

Specialty:

Orthopedic Surgery, Sports Medicine & Rehabilitation

Objective:

ICD-10:

Description:

A patient with cancer may develop localized or diffuse bone marrow necrosis (BMN). This is caused by a stasis in the blood supply to the marrow with hypoxic damage. It is considered distinct from avascular necrosis of bone. Diffuse bone marrow necrosis is often associated with a poor prognosis.

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