Description

Batrachotoxin is a highly toxic alkaloid secreted by several creatures to deter predation.


Toxicology: a group of steroidal alkaloids that affects the voltage-gated sodium channel (irreversibly opens and prevents closure)

 

Sources:

(1) frogs (Phyllobates poison-dart)

(2) birds (some tropical passerine birds)

(3) beetles

 

It action is more rapid at an alkaline pH.

 

Clinical features:

(1) convulsions

(2) muscle contractions and/or paralysis

(3) salivation

(4) respiratory paralysis

(5) cardiac arrhythmias

(6) death


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