Clinical Decision Score of Jacob et al for Predicting Mycobacterium tuberculosis Bacteremia in an HIV-Infected Patient in Uganda Presenting with Severe Sepsis
Jacob et al developed a clinical prediction rule for identifying an HIV-infected patient in Uganda with Mycobacterium tuberculosis bacteremia. The authors are from multiple hospitals in the United States and Uganda.
Patient selection: HIV-infected patient with severe sepsis in Uganda
Parameters:
(1) gender
(2) HAART
(3) absolute CD4 count per µL
(4) primary complaint on admission
(5) heart rate in beats per minute
(6) hemoglobin in g/dL
(7) serum sodium in mmol/L (mEq/L)
Parameter
Finding
Points
gender
female
0
male
2
HAART
currently taking
0
not currently taking
4
absolute CD4 count
>= 200 per µL
0
51 to 199 per µL
5
<= 50 per µL
7
primary complaint
fever
1
other
0
heart rate
< 110 beats per minute
0
110 to 139 beats per minute
1
>= 140 beats per minute
2
hemoglobin
> 10.5 g/dL
0
8.0 to 10.5 g/dL
3
6.5 to 7.9 g/dL
4
< 6.5 g/dL
5
serum sodium
> 135 mmol/L
0
130 to 135 mmol/L
1
123 to 129 mmol/L
2
116 to 122 mmol/L<
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