Description

Chordomas are rare tumors that present differently based upon location. One group occurs at the skull base along the cephalad end of the primitive notochord.


Patient selection: chordoma arising in the skull base

 

Clinical findings:

(1) abducens (cranial nerve 6) palsy

(2) palsies of lower cranial nerves

(3) headache

(4) metastasis

 

On skull X-rays there may be a lytic lesion of bone with periosteal elevation.

 

On MRI it:

(1) is hypointense on T1-weighted images

(2) is hyperintense on T2-weighted images

(3) shows contrast enhancement


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