Clinical Findings:
(1) anorexia, vomiting or nausea
(2) peripheral neuropathy
(3) weakness or poor functional status
(4) impaired alertness
(5) pericarditis
(6) ascites
(7) very low weight gain between treatments
(8) unexplained, persistent weight loss
(9) fluid retention or hypertension
(10) diarrhea
Laboratory Findings:
(1) urea reduction ratio < 65%
(2) Kt/V ratio < 1.2
(3) low serum albumin concentration (< 4 g/dL)
(4) low predialysis blood urea nitrogen concentrations (< 50 mg/dL)
(5) low predialysis serum creatinine concentration (< 5 mg/dL)
(6) persistent anemia (hematocrit < 30%) despite epoetin therapy
where:
• urea reduction ratio = 1 - ((postdialysis BUN) / (predialysis BUN))
• low serum albumin, blood urea nitrogen and/or creatinine may be indications of malnutrition
