Clinical features:
(1) usually affects older adults (age > 50 years)
(2) usually arises on a peripheral site (ear, nose, hands and/or feet)
(3) may be solitary or bilateral
(4) slow-growing and indolent
(5) without preceding patches and plaques (preceding lesions seen with mycosis fungoides)
Histologic findings:
(1) small to medium-sized CD8 positive lymphocytes
(2) diffuse dermal infiltrate with a Grenz zone from uninvolved epidermis (not epidermotropic)
(3) monoclonality
(4) CD4-negative with aberrant loss of T-cell antigens
(5) Ki-67 low (< 10%), occasionally moderate
(6) CD68 positive in Golgi apparatus (dot-like perinuclear positivity)
