Antibiotic Associated Hemorrhagic Colitis

Does the patient have a history of recent antibiotic therapy prior to the onset of the diarrhea?

Does the patient has a history of recent NSAID therapy prior to onset of the diarrhea?

Does colonoscopy show a predominantly right-sided hemorrhagic colitis that is rectal sparing?

Is a pseudomembrane present?

Has the patient responded to discontinuing antibiotic therapy and NSAIDS?

Has the patient responded to discontinuing antibiotic therapy?

Has the patient responded to discontinuing the NSAID therapy?

Are tests for Clostridium difficile negative?

Is a stool cultures positive for Klebsiella oxytoca?

Do susceptibility studies show the Klebsiella strain to be resistant to the antibiotic being administered?

Is cytoxin present in the stool?

Does the patient have signs of inflammation with leukocytosis and an elevated C-reactive protein?

Is there another diagnosis (ischemic colitis, enterotoxic E. coli, etc) that can explain the findings better?