Patient selection: orthopedic trauma patient following surgery
Parameters:
(1) age of the patient in years
(2) dementia
(3) hypertension
(4) postoperative serum H-FABP (heart-type fatty acid binding protein) in ng/mL
(5) postoperative serum sTNFR1 (soluble tumor necrosis factor 1) in ng/mL
(6) postoperative serum MK (midkine) in pg/mL
|
Parameter
|
Finding
|
Points
|
|
age of the patient
|
< 80 years
|
0
|
|
|
>= 80 years
|
1
|
|
dementia
|
no
|
0
|
|
|
yes
|
1
|
|
hypertension
|
no
|
0
|
|
|
yes
|
1
|
clinical score =
= SUM(points for the 3 parameters)
biomarker patient score =
= (2.037 * LN(H-FABP)) + (2.373 * LN(sTNFR1)) + (0.056 * LN(MK)) - 8.185
Interpretation:
• The biomarker patient score is negative if the score is < -1.05.
• The biomarker patient score is positive if the score is >= -1.05.
• minimum clinical score: 0
• maximum clinical score: 3
• A clinical score of 0 is low.
• A clinical score >=1 is high.
|
Biomarker Score
|
Patient Score
|
Risk of AKI
|
|
negative
|
low
|
low
|
|
negative
|
high
|
low to moderate
|
|
positive
|
low
|
moderate
|
|
positive
|
high
|
high
|
