Description

Jalan et al reported a score for evaluating a patient with acute-on-chronic liver failure (ACLF) for the CLIF-Consortium. The authors are from multiple institutions in Europe and members of the EASL-CLIF Consortium.


Patient selection: acute-on-chronic liver failure

 

Parameters:

(1) age in years

(2) CLIF organ failure score (CLIF-OF, from 6 to 18)

(3) WBC count in 10^9/L

 

score =

= 10 * ((0.33 * (CLIF organ failure score)) + (0.04 * (age)) + (0.63 * LN((WBC count)-2)))

 

probability of death at time "t" =

= 1 - EXP((-1) * A * EXP(B))

 

Time t

Value A

Value B

28 days

0.0022

0.0995 * (score)

90 days

0.0079

0.0869 * (score)

180 days

0.0115

0.0824*  (score)

365 days

0.0231

0.0731 * (score)

 


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