Description

Jalan et al reported a score for evaluating a cirrhotic patient with acute decompensation but without acute-on-chronic liver failure (ACLF). The authors are from multiple institutions in Europe and members of the EASL-CLIF Consortium.


Patient selection: hospitalised cirrhotic patient with acute decompensation but without acute-on-chronic liver failure

 

Parameters:

(1) age in years

(2) serum sodium in mmol/L

(3) WBC count in 10^9/L

(4) serum creatinine in mg/dL

(5) INR

 

score =

= 10 * ((0.66*LN(creatinine)) + (0.03 * (age)) + (1.71*LN(INR))+ (0.88 * LN(WBC count))-(0.05*(sodium))+8)

 

probability of death at time "t" =

= 1 - EXP((-1) * A * EXP(B))

 

Time t

Value A

Value B

90 days

0.00056

0.1007 * (score)

180 days

0.00173

0.0889 * (score)

365 days

0.00879

0.0698 * (score)

 

Performance:

• The area under the ROC curve is 0.76.


To read more or access our algorithms and calculators, please log in or register.