Suleiman et al modified the criteria of Zulini et al for classifying certainty in the diagnosis of autoimmune epilepsy.
Parameters:
(1) neuronal surface autoantibodies (NSA)
(2) response to immunotherapy
(3) GAD autoantibodies
NSA
|
GAD AutoAb
|
Response
|
Classification
|
in serum or CSF
|
NA
|
present
|
definite
|
in serum or CSF
|
NA
|
absent or unknown
|
probable
|
absent
|
present
|
present
|
probable
|
absent
|
present
|
absent or unknown
|
possible
|
absent
|
absent
|
present
|
possible
|
absent
|
absent
|
absent
|
unlikely
|
absent
|
absent
|
unknown
|
unknown
|
where:
• An unrecognized neuronal surface autoantibody might not be appreciated in this scheme.