Emancipator classified the histopathologic changes seen in IgA nephropathy and Henoch-Schonlein nephritis.
Requirement for the renal biopsy: 9 or more glomeruli
Parameters:
(1) glomerular changes other than crescents
(2) crescents
Glomerular Changes Other Than Crescents |
Glomeruli with Crescents |
Class |
none |
none |
0 |
minimal |
none |
I |
mesangial proliferation without extracapillary proliferation |
none |
II |
mesangial proliferation with extracapillary proliferation |
< 50% |
III |
mesangial proliferation with extracapillary proliferation |
50-75% |
IV |
mesangial proliferation with extracapillary proliferation |
> 75% of glomeruli |
V |
pseudomembranoproliferative glomerulonephritis |
NA |
VI |
where:
• Classes II to V may or may not show endocapillary proliferation.
Specialty: Nephrology, Clinical Laboratory, Immunology/Rheumatology