Acute Leukemia of Ambiguous Lineage refers to an acute leukemia without clear evidence of differentiation along a single lineage according to the 2008 WHO classification.
Definition: no clear evidence of differentiation following extensive evaluation using multi-parametric flow cytometry immunophenotyping
Categories
Features
acute undifferentiated leukemia (AUL)
no markers for a lineage identified, may show CD34 and/or HLA-DR